Valor nutritivo de algumas dietas artificiais para Anastrepha obliqua (Diptera, Tephritidae)

Valor nutritivo de algumas dietas artificias para Anastrepha obliqua (Diptera, Tephritidae). Algumas dietas artificias, em diferentes concentrações, foram testadas e sua eficiência foi calculada a partir do peso das pupas, do tempo para apupar e da porcentagem de empupação. Os melhores resultados foram obtidos com fermento 4,5 g/ 150 ml de dieta; os outros produtos testados foram: germe de trigo, feijão soja, leite em pó e aveia

Reconhecimento de Pessoas em Florestas utilizando monitoramento de imagens em tempo real e métodos inteligentes

A Visão Computacional é uma ferramenta muito útil para o monitoramento e reconhecimento de pessoas em uma cena. Essa tarefa é realizada por meio da análise automática e inteligente de imagens. Para isso utiliza o Processamento Digital de Imagens para a extração dos objetos de interesse na cena, além de métodos de Aprendizado de Máquina, que torna possível detectar a invasão de pessoas na cena. Este trabalho propõe o experimento entre métodos existentes nestas áreas de estudo

Reconhecimento de Pessoas em Florestas utilizando monitoramento de imagens em tempo real e métodos inteligentes

A Visão Computacional é uma ferramenta muito útil para o monitoramento e reconhecimento de pessoas em uma cena. Essa tarefa é realizada por meio da análise automática e inteligente de imagens. Para isso utiliza o Processamento Digital de Imagens para a extração dos objetos de interesse na cena, além de métodos de Aprendizado de Máquina, que torna possível detectar a invasão de pessoas na cena. Este trabalho propõe o experimento entre métodos existentes nestas áreas de estudo

Towards a Vaccine Against Rheumatic Fever

Rheumatic fever (RF) is an autoimmune disease which affects more than 20 million children in developing countries. It is triggered by Streptococcus pyogenes throat infection in untreated susceptible individuals. Carditis, the most serious manifestation of the disease, leads to severe and permanent valvular lesions, causing chronic rheumatic heart disease (RHD). We have been studying the mechanisms leading to pathological autoimmunity in RF/RHD for the last 15 years. Our studies allowed us a better understanding of the cellular and molecular pathogenesis of RHD, paving the way for the development of a safe vaccine for a post-infection autoimmune disease. We have focused on the search for protective T and B cell epitopes by testing 620 human blood samples against overlapping peptides spanning 99 residues of the C-terminal portion of the M protein, differing by one amino acid residue. We identified T and B cell epitopes with 22 and 25 amino acid residues, respectively. Although these epitopes were from different regions of the C-terminal portion of the M protein, they showed an identical core of 16 amino acid residues. Antibodies against the B cell epitope inhibited bacterial invasion/adhesion in vitro. Our results strongly indicated that the selected T and B cell epitopes could potentially be protective against S. pyogenes

Competencias transversales para el aprendizaje en estudiantes universitarios

El presente artículo da cuenta de la experiencia que se está realizando, desde el año 2003, en la Universidad de Los Lagos de Osorno; la que se dice relación con el Programa de Fortalecimiento de Competencias Transversales para el aprendizaje. Dentro de él se fortalecen las habilidades cognitivas y socioafectivas indispensables para enfrentar de mejor manera los desafíos que impone el aprendizaje en la universidad, lo que también será de utilidad en la vida profesional. Se pretende apoyar el proceso de integración de los estudiantes a la vida universitaria y su desempeño futuro, estableciendo un sistema de apoyo a los alumnos iniciales, para compensar los niveles de manejo insuficiente de competencias cognitivas para el aprendizaje, a través de la implementación de módulos de trabajo

High-risk HPV infection after five years in a population-based cohort of Chilean women

<p>Abstract</p> <p>Background</p> <p>The need to review cervical cancer prevention strategies has been triggered by the availability of new prevention tools linked to human papillomavirus (HPV): vaccines and screening tests. To consider these innovations, information on HPV type distribution and natural history is necessary. This is a five-year follow-up study of gynecological high-risk (HR) HPV infection among a Chilean population-based cohort of women.</p> <p>Findings</p> <p>A population-based random sample of 969 women from Santiago, Chile aged 17 years or older was enrolled in 2001 and revisited in 2006. At both visits they answered a survey on demographics and sexual history and provided a cervical sample for HPV DNA detection (GP5+/6+ primer-mediated PCR and Reverse line blot genotyping). Follow-up was completed by 576 (59.4%) women; 45 (4.6%) refused participation; most losses to follow-up were women who were unreachable, no longer eligible or had missing samples. HR-HPV prevalence increased by 43%. Incidence was highest in women < 20 years of age (19.4%) and lowest in women > 70 (0%); it was three times higher among women HR-HPV positive versus HPV negative at baseline (25.5% and 8.3%; OR 3.8, 95% CI 1.8-8.0). Type-specific persistence was 35.3%; it increased with age, from 0% in women < 30 years of age to 100% in women > 70. An enrollment Pap result ASCUS or worse was the only risk factor for being HR-HPV positive at both visits.</p> <p>Conclusions</p> <p>HR-HPV prevalence increased in the study population. All HR-HPV infections in women < 30 years old cleared, supporting the current recommendation of HR-HPV screening for women > 30 years.</p

Distinct Roles for Neuropilin1 and Neuropilin2 during Mouse Corneal Innervation

Trigeminal sensory innervation of the cornea is critical for protection and synthesis of neuropeptides required for normal vision. Little is known about axon guidance during mammalian corneal innervation. In contrast to the chick where a pericorneal nerve ring forms via Npn/Sema signaling, mouse corneal axons project directly into the presumptive cornea without initial formation of an analogous nerve ring. Here we show that during development of the mouse cornea, Npn1 is strongly expressed by the trigeminal ganglion whereas Npn2 is expressed at low levels. At the same time Sema3A and Sema3F are expressed in distinct patterns in the ocular tissues. Npn1sema−/− mutant corneas become precociously and aberrantly innervated by nerve bundles that project further into the corneal stroma. In contrast, stromal innervation was not affected in Npn2−/− mutants. The corneal epithelium was prematurely innervated in both Npn1sema−/− and Npn2−/− mutants. These defects were exacerbated in Npn1sema−/−;Npn2−/− double mutants, which in addition showed ectopic innervation of the region between the optic cup and lens vesicle. Collectively, our data show that Sema3A/Npn1 and Sema3F/Npn2 signaling play distinct roles and both are required for proper innervation of the mouse cornea